Genetic Testing
VCP disease is caused by a pathogenic variant of the VCP gene.
It can cause multiple diseases including inclusion body myopathy, Paget's disease of bone, and frontotemporal dementia.
Consultation with a genetic counselor before and after genetic testing is recommended.
Why is VCP Genetic Testing Important?
VCP disease is a genetic, adult-on-set, autosomal dominant disease. That means there’s a 50% chance a parent can pass their mutated VCP gene to a child.
Only a genetic test can confirm VCP disease.
VCP Genetic Testing Options
Several VCP genetic testing options are available.
Physicians can order full sequencing of the VCP gene or targeted sequencing of exons where mutations are most often found.
Free genetic testing is available through Perkin Elmer
The VCP panel is available through the Limb Girdle Muscular Dystrophy link.
Invitae's Detect Muscular Dystrophy panel may be free of charge for those who qualify.
The Comprehensive Neuromuscular Disorders panel includes the VCP gene.
Dante Labs offers whole genome sequencing.
A comprehensive test that covers 98% of the whole genome.
Disclaimer: Cure VCP Disease, Inc. is providing the above information to the best of our knowledge. The organization is not advocating for any particular company or method. Consultation with a genetic counselor or clinical geneticist prior to and following testing is recommended.